Depo-Provera is an injectable contraceptive. A 2024 study published in The BMJ associated prolonged use with an increased risk of intracranial meningioma, and lawsuits have followed.
Overview
Depo-Provera (medroxyprogesterone acetate) is a prescription injectable contraceptive, typically administered once every three months. It is manufactured by Pfizer.
In March 2024, a study published in The BMJ reported an association between prolonged use of injectable medroxyprogesterone acetate and an increased risk of intracranial meningioma — a tumor that forms in the membranes surrounding the brain and spinal cord. Following that research, lawsuits have been filed alleging that patients were not adequately warned of this potential risk.
An association identified in a study is not the same as proof that the medication caused any individual's condition. This page is educational only and does not diagnose any condition or assess any legal claim.
Reported concerns
- Diagnosis of intracranial meningioma after prolonged Depo-Provera use
- Headaches that are new, persistent, or worsening
- Vision changes or loss
- Hearing changes or ringing in the ears
- Seizures
- Surgery, radiation, or ongoing monitoring for a meningioma
Who may want to learn more
You may want to request a free review if:
- You received Depo-Provera injections, typically for a year or longer.
- You were later diagnosed with a meningioma.
- You sought treatment such as monitoring, surgery, or radiation.
These are general informational prompts, not a determination that you have a claim. Eligibility is evaluated by independent attorneys.
Frequently asked questions
Should I stop taking Depo-Provera?
Do not make any change to your medication without speaking to your healthcare provider. This page is for information only and is not medical advice.
What did the 2024 study find?
Researchers reported a statistical association between prolonged use of injectable medroxyprogesterone and an increased risk of intracranial meningioma. An association is not the same as proven causation for any individual.
What are the lawsuits about?
They generally allege a failure to adequately warn patients of a potential meningioma risk. These are allegations and have not been proven; results vary by case.
References
- Roland N, et al. The BMJ (2024). Study reporting an association between prolonged injectable progestogen use and intracranial meningioma.